Gene Expression Dissertation Topics



August of 2017

Novel Cell Surface Anchoring Mechanism of Prokaryotic Secreted Protein - Mohd Farid Abdul Halim, Ph.D.

The Genetic Architecture Underlying Rapid Seasonal Evolution in Natural Populations of Drosophila melanogaster - Emily Behrman, Ph.D.

Developmental Functions of MIR156 and MIR157 in Arabidopsis- Jia He, Ph.D.

Dedifferentiation of Cytotoxic Lympthocyte into Central Memory CD8+T Cells:  Lessons from Antiviral T-Stem Cells on the Architecture of Aging and Immunotherapy - Jonathan Johnnidis, Ph.D.

 

Class of 2017

Proteolytic Activation by ADAMTS3 Defines Distinct Mechanisms of Lymphangiogenesis Mediated by VEGFC and VEGFD - Hung Bui, Ph.D.

Transcript Diversity in the Protozoan Parasite Toxoplasma Gondii - Maria Diaz, Ph.D.

Plant-soil Feedback and Succession in Heavy Metal Soils - Lee Dietterich, Ph.D.

Genome Editing Approach to Uncover Microtubule-Actin Crosslinking Factor (MACF1) Essential Domains in Establishing Oocyte Polarity and Nuclear Positioning - Matias Escobar, Ph.D.

Investigation of the Spatiotemporal Dynamics of cAMP and PKA Signaling and the Role of HCN4 Subunits in Anxiety-Related Behavior and Memory - Vincent Luczak, Ph.D.

The C-REL Transcription Factor Controls Metabolism and Proliferation of Human T Cells - George Luo, Ph.D.

Space, Time and Change: Investigations in Soil Bacterial Diversity in the Montane Steppe of Mongalia - Aurora MacRae-Crerar, Ph.D.

Population Genetics of Borrelia Burgdorferi in the Eastern and Midwestern United States - Stephanie Seifert, Ph.D.

Hypermutability in Asexuals: Investigating the Effects of Deleterious Mutations - Tanya Singh, Ph.D.

Class of 2016

Molecular and Cellular Approaches Toward Understanding Dynein-Driven Motility - Swathi Ayloo, Ph.D.

Cell Biology of Cheating - Mechanisms of Chromosomes Segregation during Female Meiosis - Lukas Chmatal, Ph.D.

Detecting Selection on Noncoding Nucleotide Variations: Methods and Applications - Yang Ding, Ph.D.

Short Term Adult Plasticity in Drosophila melanogaster and its Role in Climatic Adaptation - Vinayak Mathur. Ph.D.

A Study of the Role of Gata6 in Definitive Endoderm Specification and β Cell Functionality by Genome Engineering of the Pluripotent Stem Cells - Amita Tiyaboonchai, Ph.D.

Phenotypic Variation in the Dogwhelk, Nucella lapillus: an Integration of Ecology, Karyotype and Phenotypic Plasticity - Katie Vazquez, Ph.D.

Genomic, Evolutionary and Functional Analyses of Diapause in Drosophila melanogster - Xiaqing Zhao, Ph.D.

Selective Forces that Shape the VLS Antigenic Variation System in Borrelia Burgdorferi - Wei  Zhou, Ph.D.

 

 

Class of 2015

 A Role of SWI/SNF Complex in ABA-dependent Drought Responsive Gene Expression in Arabidopsis thaliana - Soon Ki Han, Ph.D.

Mechanisms Underlying the Role of Drosophila TIMELESS in the Molecular Clock and in the Circadian Response to Light - A Reum Jang, Ph.D.

The Genetic Basis of Phenotypic Plasticity in Natural Populations of Drosophila - Katherine O'Brien, Ph.D.

Spatial and Temporal Variation in Wild Pollination Services in the Mongolian Steppe - Dan Song, Ph.D.

 Promoting T-snare Binary Complex Assembly and Membrane Fusion by the Exocyst Protein Sec3 - Peng Yue, Ph.D.

Novel Regulators in the Germline Stem Cell Niche of Drosophila Testis - Qi Zheng, Ph.D.

Class of 2014

Change and Impact of microRNA Modification with Age in Drosophila melanogaster - Masashi Abe, Ph.D.

Mitotic Kinases in Meiosis - Olga Davydenko, Ph.D.

Higher-Order Chromatin Organization in Hematopoietic Transcription - Wulan Deng, Ph.D.

Effects of Temperature on Global Gene Expression in Natural Strains of Budding Yeast - Hoa Giang, Ph.D.

Regulators of Mouse and Human Beta Cell Proliferation - Yang Jiao, Ph.D.

Trial-by-Trial Coding of Instructive Signals in the Cerebellum:  Insights from Eyeblink Conditioning in Mice - Farzaneh Najafi, Ph.D. 

The Molecular Mechanism of Synaptic Tagging and Capture - Jung Whan Park, Ph.D.

Dynamics and Fate of the Inner Membrane complex in Toxoplasma gondii - Dinkorma Toure Ouologuem, Ph.D.

Regulation of Adipose Tissue Development and Function by Nuclear Receptors PPARg and Rev-erba - Fenfen Wang, Ph.D.

Towards a Better Understanding of Nonstructural Carbohydrate Storage and Carbon Limitation in Trees - Erin Wiley, Ph.D.

Exo70 Generates Membrane Curvature for Morphogenesis and Cell Migration - Yuting Zhao, Ph.D.

 

Class of 2013

Higher-order Chromatin Organization in Hematopoietic Transcription - Wulan Deng, Ph.D.

Multiscale Analyses of the Population Structure of Triatoma infestans in an Urban Area - Erica Foley, Ph.D.

The Impact of Terrestrial Dissolved Organic Carbon on Stream Ecosystem Function through an Investigation of Hydrologic Sources in White Clay Creek, PA - Christine McLaughlin, Ph.D.

 Biology of Respiratory and Cardiac Functional Deterioration in a Translational Model for Duchenne Muscular Dystrophy - Andrew Mead, Ph.D.

 Species-Specific Effects on the Oxygen Isotope Ratio of Tree-Ring Cellulose - Xin Song, Ph.D.

 The interplay between Lewy body-like alpha-synuclein aggregates and protein degradation pathways in a cell-based model of Parkinson’s disease - Selcuk Tanik, Ph.D.

 Structure and Function of H. volcanii flagella - Manuela Tripepi, Ph.D.

 

Class of 2012

Investigation of the Methane Cycle and Associated Microbial Community of a Pine Forest Soil- Emma Aronson, Ph.D.

A Role for Late Meristem Identity2 in the Reproductive Development of Arabidopsis - Jennifer Pastore, Ph.D.

The Molecular Mechanism of Vegetation Phase Change: Regulation of miR156 Expression and Action - Li Yang, Ph.D.

Meiotic Origins of Maternal Age-Related Aneuploidy - Teresa Chiang, Ph.D.

Decoding Cytochrome C Oxidase Biogenesis: New Insights into Copper Trafficking - Nursel Ekici, Ph.D.

Evolution of Molecular Function in Mammalian Neurons - Chantal Francis, Ph.D.

The Cytoskeletal Mechanisms of Cell-Cell Junction Formation in Endothelial Cells - Matthew Hoelzle, Ph.D.

Microrna Precursor Programmed Silencing Complex Assembly and Regulatory Pathways in Mammals - Xuhang Liu, Ph.D.

The Role of EPAC Signaling in Memory Consolidation and Sleep Deprivation - Nan Ma, Ph.D.

Behavior and Socioendocrinology of Adult and Male Rhesus Macaques of Cayo Santiago - Maria Rakhovskaya, Ph.D.

Molecular Insight into Mechanisms of CAG-Repeat RNA Toxicity in Polyglutamine Disease from Drosophila - Shin-Yi Shieh, Ph.D.

The Evolution of a High Mutation Rate and Declining Fitness in Asexual Populations - Christopher Gentile Ph.D.

Selection on Mutators in Experimental Saccharomyces Cerevisiae Populations: Recombination, Clonal Interference, and the Evolution of Mutation Rates - Yevgeniy Raynes, Ph.D.

 

Class of 2011

 Socioecology, Acoustic Communication and Demography of Asian Elephants in Sri Lanka - Shermin deSilva, Ph.D.

The Role of Exocyst in Exocytosis and Cell Migration - Jianglan Liu, Ph.D.

YY1 Controls Immunoglobulin Class Switch Recombination and Nuclear Aid Levels - Kristina Zaprazna, Ph.D.

Mechanisms of HDAC2 Function in the Regulation of Adult Cardiac Hypertrophy and Embryonic Myocyte Proliferation - Wenting Zhu, Ph.D.

Actin-Independent Mechanisms of Targeting Formin mDIA2 to the Plasma Membrane - Roman Gorelik, Ph.D.

Roles of Protein Factors in Regulation of Imprinted Gene Expression - Shu Lin, Ph.D.

Functional Plasticity of Hippocampal Glutamatergic Synapses in Development and Disease - Xiaoyu Peng, Ph.D.

Physiological Bases of Plant Shrinkage and its Demographic Implications - Roberto Salguero-Gomez, Ph.D.

 

Class of 2010
Unplugged/Musk Signaling Coordinates Pre- and Post-synaptic Development at the Neuromuscular Junction - Lili Jing, PhD

Spatially Varying Selection on Shell Color Phenotype in the Flat Periwinkle Littorina Obtusata - Megan Phifer-Rixey, PhD

Niche Partitioning Among Arbuscular Mycorrhizal Fungi and Consequences for Host Plant Performance - Jennifer H. Doherty, PhD

Microrna Pathways Modulate Aging and Neurodegenerative Diseases - Nan Liu, PhD

The Rab3A Locus: Studies of Neuronal Expression and Effects on Behavior - Rui Liu, PhD

The Evolutionary Genetics of Life History in Drosophila Melanogaster - Annalise Bloss Paaby, PhD

Using Evolutionary Genomics to Elucidate Parasite Biology and Host-Pathogen Interactions - Lucia Peixoto, PhD

 

Class of 2009
Characterizing the Role of the Exocyst Component EX070 in Exocytosis and Actin Dynamics in Budding Yeast Saccharomyces Cerevisiae - Bing He, PhD

Slit Down-Regulates CRGAP Function to Mediate Axon Repulsion in the Embryonic Drosphila CNS - Ming Li, PhD

Molecular Basis of Chve Function in Sugar Binding and Virulence in Agrobacterium Tumefaciens - Fanglian He, PhD

Spatial and Temporal Variation in Streambed Bacterial Community Composition and Correlation with Einvironmental Variables and Disturbance - Karen Rowley Hogan, PhD

Squint, The Arabidopsis Ortholog of Cyclophilin40, Affects RNA Silencing- Michael Smith, PhD

Spatial Regulation of CDC42 by its GTPase-Activating Proteins RGA1 and BEM2 in Budding Yeast Saccharomyces Cerevisiae - Zongtian Tong, PhD

 

Class of 2008

Molecular and Cellular Mechanism of Axon Guidance During Visual System Development in Zebrafish - Michael Gyda, PhD

Phylogeny and Evolution of Prokaryotic Genomes - Fan Ge, PhD

The Role of the Exocyst Complex in Polarized Exocytosis - Puyue Wang, PhD

Evolutionary Ecology of Host Plant Use by an Insect Herbivore in a Highly Seasonal Neotropical Dry Forest - Salvatore Agosta, PhD

Variation Among Dogwhelks (Nucella lapillus) Modifies Predator-prey Interactions within Intertidal Assemblages - Jonathan Fisher, PhD

Peeking into the Black Box: The Structure and Function of Soil Microbial Communities in Response to Increasing Nitrogen Availability - Richard Lucas, PhD

Taxonomic and Functional Diversity of AM Fungi in Serpentine and Prairie Grasslands - Baoming Ji, PhD

Dissecting Different Modules of Cytochrome C Maturation in Rhodobacter Capsulatus- Serdar Turkarslan, PhD

Role of Exocytosis in Cell Polarization - Xiaoli Sun, PhD

 

Class of 2007

The Analysis of the PI3K/AKT Pathway in Human Ovarian Cancer with a Combination of Genomic and Genetic Appoaches - Jia Huang, PhD

Examination of the Twin-Arginine Translocation Pathway in Bacteria and Archaea - Kieran Dilks, PhD

Spatial Orientation in Columbian Ground Squirrels (Spermophilus Columbianus) - Anna Vlasak, PhD

From Protein to RNA: Study of SCA3 Polyglutamine Disease in Drosophila - Lingbo Li, PhD

Novel Insignts Into Vir Gene Regulation in Agrobacterium Tumefaciens - Gauri Nair, PhD

Spatial and Genetic Patterns of Crane Flies (Diptera: Tipuloidea) from Lake Hovsgol Region, Mongolia - Bazartseren Boldgiv, PhD

Aging in Plants at Multiple Scales - Lori Spindler, PhD

Metabolic Pool, Metabolic Rates and Diapause in Drosophila Melanogster - Christine Wills, PhD

Phylogenetics and Diversification of the Neotropical Serrasalminae (Ostariophysi: Characiformes) - Wasila Dahdal, PhD

This collection was named as Theses and Dissertations--Toxicology before Jan. 1, 2015.

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Theses/Dissertations from 2018

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MULTIVARIATE ANALYSIS TO IDENTIFY POTENTIAL BIOMARKERS FOR PROGNOSIS AND TREATMENT RESISTANCE IN HEAD AND NECK CANCER PATIENTS, Christina Ann Wicker

Theses/Dissertations from 2017

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EFFECTS OF CHROMIUM ON MOUSE SPLENIC T LYMPHOCYTES AND EFFECTS OF ETHANOL EXPOSURE DURING EARLY NEURODEVELOPMENT ON BEHAVIORS IN MICE, Lu Dai

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NUCLEOTIDE EXCISION REPAIR: IMPACTS OF ENVIRONMENTAL CARCINOGENS AND ITS ROLE IN CANCER SUSCEPTIBILITY IN APPALACHIAN KENTUCKY, Nathaniel C. Holcomb

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Metabolic Reprogramming of Human Lung Cancer Cells and Ex vivo Tissues Revealed by UHR-FTMS Analysis of Small Amino and Carboxyl Metabolites, Ye Yang

Theses/Dissertations from 2016

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ROLE OF SULFIREDOXIN INTERACTING PROTEINS IN LUNG CANCER DEVELOPMENT, Hedy Chawsheen

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Overcoming Treatment Resistance in Heterogeneous Tumors, Nikhil Hebbar

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EXPLORATION OF THE SRX-PRX AXIS AS A SMALL-MOLECULE TARGET, Murli Mishra

Theses/Dissertations from 2015

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PHARMACOLOGIC INDUCTION OF THE MELANOCOTIN 1 RECEPTOR (MC1R) PATHWAY PROVIDES PROTECTION AGAINST SUNBURN AND ENHANCES EXPRESSION OF ANTIOXIDANT ENZYMES IN THE SKIN, Alexandra Amaro-Ortiz

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ROLE OF CAVEOLIN-1 AND NRF2 IN NUTRITIONAL MODULATION OF PCB TOXICITY, Michael C. Petriello

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CROSS-TALK BETWEEN THE TUMOR SUPPRESSORS PAR-4 AND P53, Tripti Shrestha Bhattarai

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LOSS OF MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1 (MRP1/ABCC1) POTENTIATES DOXORUBICIN-INDUCED CARDIOTOXICITY IN MICE, Wei Zhang

Theses/Dissertations from 2014

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MRP1: A TARGET FOR HEMATOPOIETIC STEM CELL DISEASES, Cassandra Reiling

Theses/Dissertations from 2013

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EFFECTS OF CELLULAR HETEROGENEITY AND IMMUNE CELLS IN ANGIOTENSIN II-INFUSED HEMORRHAGED ASCENDING AORTAS, Kyung Sik Jung

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REDOX-REGULATED RELB-AR AXIS MEDIATES PROSTATE SPECIFIC ANTIGEN EXPRESSION: INSIGHT IN PROSTATE CANCER RESPONSE TO RADIATION THERAPY, Lu Miao

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COFILIN NAVIGATES CELLULAR CYTOSKELETON AND INVASION RESPONSES TO TGF-β TOWARDS PROSTATE CANCER METASTASIS, Joanne Collazo Santiago

Theses/Dissertations from 2012

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MnSOD AND AUTOPHAGY IN PREVENTION OF OXIDATIVE MITOCHONDRIAL INJURIES INDUCED BY UVB IN MURINE SKIN, Vasudevan Bakthavatchalu

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PHYSIOLOGICAL AND TOXICOLOGICAL ROLES OF ABC TRANSPORTERS IN CELLULAR EFFLUX OF SUBSTRATES, Donna J. Coy

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RELATIONSHIPS BETWEEN TELOMERIC SEQUENCES AND STRUCTURES, DNA REPLICATION, AND THE FUNCTION OF THE WERNER SYNDROME PROTEIN, Deanna Edwards

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NOVEL MECHANISM LEADING TO MISMATCH REPAIR DEFICIENCY AND MUTATOR PHENOTYPE, Janice Ortega Rodríguez

Dissertations from 2011

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ANALYSIS OF DIFFERENTIAL GENE EXPRESSION AND ALTERNATIVE SPLICING IN THE LIVER AND GASTROINTESTINAL TRACT IN THE LACTATING RAT, Antony Thomas Athippozhy

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IDENTIFICATION OF ACTIVITIES INVOLVED IN CAG/CTG REPEAT INSTABILITY, Nelson Lap Shun Chan

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GENOTOXIN-INDUCED ACETYLATION OF THE WERNER SYNDROME PROTEIN (WRN) AND EFFECT ON ITS DNA METABOLIC FUNCTION, Enerlyn Meliza Lozada Santiago

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ANDROGEN INCREASES ANGIOTENSIN RECEPTOR TYPE 1A ON SMOOTH MUSCLE CELLS TO PROMOTE ANGIOTENSIN II-INDUCED ABDOMINAL AORTIC ANEURYSMS, Xuan Zhang

Dissertations from 2010

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INHIBITION OF CHOLESTEROL SYNTHESIS BY POLICOSANOL, Subhashis Banerjee

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POLYCHLORINATED BIPHENYL-INDUCED ENDOTHELIAL CELL DYSFUNCTION AND ITS MODULATION BY DIETARY LIPIDS, Zuzana Majkova

 

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